Tuesday, December 18, 2012

Christmas Letter 2012


Goodlett Family 2012 Collage  

I suspect that like me, you all are having a hard time getting past the massacre of 20 innocent children in Newtown, CT. The innocence of my own kids at Christmas time when they were that age leaves me unable to get this sadness out of my mind. For me the idea of a child’s innocence is seared into my memory from one Christmas morning when the boys were about four and five years old. Mint ran down stairs and on seeing a construction set displayed on the floor yelled to his brother “Graham! He really did come. He really did come!” …

Of course, guns don’t kill people. People kill people. This time in Connecticut and earlier this year in Colorado and before that in Virginia, and before that again in Colorado … mentally disturbed young men massacred innocents. So while some form of gun control is needed, its also clear to me that President Reagan’s vision that communities and local governments would take care of their mentally ill isn’t working. His actions abolished the provisions of the National Mental Health Systems Act that were signed into law by President Carter and stopped existing government aid to care for the mentally ill. So while its true that the lethality of readily accessible weapons is part of the problem, our national discussion has to include mental health care reform because the combination of a mentally deranged person with an assault weapon is like yelling fire in a crowded theater. It should be illegal. 

Mental health issues are something our family hears about on a frequent basis from Donna who has continued her efforts working with the homeless community this past year. From my perspective I can see that it’s rather easy to get them the food and shelter they need, but nearly impossible to do more. Doing more requires establishing relationships to help them get out of their behavioral loops, but such meaningful relationships cost time and money that local governments and charities lack. Most homeless are not mentally ill, but simply down on their luck. Others though are in deep dark emotional holes that they can’t climb out of alone. Climbing out requires individualized help for which society currently has no answer beyond family, community and faith organizations all of which are overwhelmed. Barring requiring a license to reproduce, which would be more controversial than gun control, teaching people how to be good parents would help a bit with some of the homeless issues we have, but not mental illness. Many of the homeless simply had bad examples set by their own parents that in turn sent them spiraling down poor behavioral paths. Most are really good people who are down on their luck and can’t get ahead in this economy.
Donna and Graham at HiLife for dinner
While one can argue that being a good parent is the most important job we do for society, the training for parenting is as haphazard as genetic recombination. No license is required to be a parent like is needed for driving a car, but doing both badly is dangerous to society. Unfortunately, it is often the case that being parented well depends in large part on the luck of being born to good parents. I still marvel at the apparent randomness in genetic recombination that gave us our boys. Parents with a dozen kids will tell you the same thing that each one is unique. From a scientific perspective even identical twins raised in the same household will have unique differences. With our boys who don’t look alike, its easy to see the differences. One is artistic and gregarious, while the other is logical almost to a fault. We can see these traits in ourselves, but there are no hard stops between the traits. In Graham’s case his phenotype is randomly matched to his middle name, Robinson, which was my Mother’s maiden name. Grandpa Robinson was a bit of a math genius from the back woods of Mississippi. Like all my Grandparents, he didn’t finish high school. He did however become a master automobile mechanic, which after being drafted saved him going to Europe in WWII, and later an ironworker. He had an inherent understanding of math and logic that you cannot teach, nor can hours of parents helping with homework instill. Recently, the argument of which is more important nature or nurture has been turned on its head by the science of epigenetics. There are now many documented examples where nurture, by which I mean here being a good parent, is much more important than nature, i.e. your genetic make up. In fact this science is beginning to explain some of the old wive's tales of inherited traits skipping generations. To catch up on this, I recommend you read “The Epigenetics Revolution” by Nessa Carey.
David eating in Baltimore's Little Italy
Not so random were a bunch of E’s (same as old-school F’s) that showed up recently on Graham’s new-school, online real time grade report. Being analytical, he had a perfectly logical explanation. He calculated that because his math homework only counted for 30% of his grade he could afford to take some E’s on homework assignments. He rationalized these omissions by explaining that 1) he already knew how to do the assignments for that topic and so they were a waste of his precious time, 2) he could explain them to everyone in the class better than even the teacher and 3) doing so would hurt neither his grade nor his education …… tsk, tsk, tsk. While I appreciated the logic, I made an on the spot correction to his innocence in rationalizing. Of course this is one way innocence is lost – jaded parents who superimpose their learned behavior on kids – or try to. In this case I am at least recording his feat to be feted by him at a later date, but I do appreciate his time management skills because I make those type decisions every day.
David and Graham eating at the bar at the Hilife in Ballard
In another testament to parents being more “correct” than not, Mint joined the drum line and the school’s marching band. After five years of trap set lesson, we encouraged him to get involved in the music program when he started high school. “Life’s not a spectator sport” he heard me say over and over. In spite of or because of my parenting skills, when he started 9th grade I had to make him sign up for the percussion class. In hindsight this was my last lesson applied by force with him, but in my defense I knew that he might need an easy A. I won the battle, but he refused to try out for jazz band or marching band even when his older classmates encouraged him. At the end of 10th grade the rules for being in percussion class changed and he was forced to try out for drum line or leave the class. For some reason – maybe he liked being in the class after all? - he tried out for and made the drum line. While he didn’t make the premier snare position he wanted, this came to us as no surprise. In preparation for the try out he played hours and hours of xbox and only the night before the try out went over snare parts for about 30’. When I asked about his preparation he exclaimed …. ”whaddaya mean I didn't prepare well? I worked for an hour or more!” … Fast-forward to the end of Summer 2012 when tryouts happened again for those seeking redemption and the same game plan produced the same outcome - a bass drum slot. There is something similar going on with math, but then I didn’t quite get math or music sorted until college. So, I don’t want to say much knowing that neither my apple nor his fell too far from the tree of reproductive randomness.
Young David in Turku

Young David and I spent a month away from Mom and Graham this year. Three weeks in Turku, Finland and a week in Dubrovnik, Croatia. For me it was mostly “work”. Not my Dad’s definition of work, but work all the same. When asked by his Mom what did he like about Finland he replied … “the pickled onions on hamburgers and the blondes”. Coming from Seattle, which is the 5th whitest city in the US including nearly 40% Asians, the preponderance of blondes in Finland was probably shocking right off the plane. The pickles I can’t explain except that the Finns even make pickled herring taste good. In Croatia we swam every day in the crystal clear, cold sea and all signs of his Seattle-based sinus problems dried up. We also had our first Father-Son beer moment. Or I could say that I had a beer with my sandwich and he had a sandwich with his beer. Regardless, during this week I had a glimpse of the Man who will soon emerge from the Boy and I liked what I saw. Besides the pickled onions and blondes in Finland, in Croatia he gained a taste for fish, which also is no surprise because in Croatia they do fish right.
Dave and Donna on the Piazza del Campo, Siena
Some of you will have heard that next year we are moving to Baltimore. After nearly 20 years in Seattle, I never imagined leaving. The School of Pharmacy at the University of Maryland – Baltimore (aka UMB; www.pharmacy.umaryland.edu) though had other ideas. After nearly two years of back and forth discussions, I finally agreed that the best thing for both parties was to leave the School of Pharmacy at the University of Washington (sop.washington.edu) where I have been for nine years.  Part of the long time in discussions included trying to convince the family to move. Convincing the boys was easy because they didn’t really understand what they were agreeing to J. That’s not completely true, but given that we don’t move until July of 2013 our visit in April 2012 was so far away that they probably didn’t quite get the reality of the visit and move. Regardless, all of us enjoyed our tour because the folks at UMB showed us wonderful hospitality and the locals we met really loved to talk about their city. This despite the dangerous reputation of Baltimore that dates back to the white-flight days of the 70s and more recently the TV show “The Wire”.  For the record, I’ve not seen that show and probably won’t until I move there! The real challenge of moving a laboratory and a family without dropping the ball on either is now a reality for us. The lab has already started the transition.

Dave and Donna 25 years on
Donna and I had time to reflect on the future move and 25 years of marriage when in August when we went once again to Siena, Italy for a scientific conference and Turku, Finland. We also spent a day in Milan shopping and site seeing as well as a day in Helsinki on the way home. The week spent in Turku opened her eyes to the Finns who are at first glance are quite reserved. For example, after walking me into the lab each day she said “No one looks at you or even smiles.” For Americans who are in large part overly friendly to strangers, this military-like coming and going bothered her. However, after dinner in the homes of a few Finns she realized they are pretty much the same when it comes to hospitality but all business when it comes to to’ing and fro’ing. If you’re wondering what I am doing in Finland, you can read more about it here http://goodlett.proteomics.washington.edu and below that even is a link to a farewell lecture I gave to a local mass spectrometry group. We are excited and apprehensive about our fourth cross-country move, but I’m certain all will be well in the end.

That’s probably enough reviewing for this year. When I started to look for photos form the year, it seemed that most were of us at dinner. Maybe we eat out too much? Anyway, we wish you all a happy holiday season and prosperous new year. 

Dave, Donna, David The Younger, Graham and Trixie The 100 lb Lap Dawg.

David the Younger after swimming in Cavtat Harbor

Dave the Elder and Graham at Chinooks - 
Fisherman's Terminal, Ballard